How Subcellular Localization of Alpha Particles Impacts Cytotoxicity & Radiotherapeutic Efficacy

• Linking decay kinetics to cellular phenotype to refine dose-response predictions
• Integrating PK–PD and radiobiology models for more accurate preclinical translation
• Optimizing preclinical dosing strategies based on mechanistic insights

Speakers:

Mark Sellmyer

Assistant Professor

University of Pennsylvania