Engineering High-Fidelity Theranostic Pairs with Covalent Radiohalogens (F-18/I-131/At-211) to Improve Biodistributi

  • Designing covalent radiohalogen therapeutics with matched diagnostic–therapeutic pairs to improve predictive biodistribution and translational confidence
  • Overcoming traditional limitations of chelated radiometals by reducing off-target accumulation and enabling blood-brain barrier penetration
  • Presenting preclinical imaging and efficacy data showing remarkable tumor control and favorable safety profiles across small molecule and bioligand-tagged platforms