Modulating Tumor Microenvironment– Mediated Resistance Mechanisms to Enhance Radiotherapy Response in Preclinical Models

  • Characterizing TME-driven resistance phenotypes, including autophagy, senescence, oxidative stress, angiogenesis, and immune modulation
  • Mapping key signaling pathways linking TME dynamics to radioresistant cellular states
  • Targeting the TME with preclinical interventions