Preclinical Evaluation & Optimization of a Multi-Specific Targeting Peptide for Radioligand Therapy

  • Scientific rationale for TwoStep Therapeutics’ multi-specific targeting agent (PIP) and how it enables broad applicability across solid tumors
  • Comparing the data from a single vs multitargeted approach to highlight the rationale of multi-specific targeting
  • Optimization of the PIP-Radio Conjugate for RLT: approach and learnings to improve biodistribution and tumor retention