Alessandro Mascioni
Director, Targeting Technology Research Telix Pharmaceuticals
Seminars
Wednesday 22nd July 2026
Lowering Off‑Target Uptake in Biologic Radiopharmaceuticals through Protein Engineering
11:00 am
- Utilizing intracellular trapping to prevent isotope and daughter escape, strengthening tumor retention
- Providing a mechanistic basis for safer and more effective application of alpha emitters
- Leveraging tumor-specific metabolic activity to achieve sufficient radioconjugate accumulation