Kirstin Zettlitz

Join your colleagues for a deep-dive discussion in smaller groups to map out the next generation of TRP targets. You will brainstorm high-potential clinical candidates and cross-pollinate ideas from the ADC space to sharpen selection strategy before sharing your table’s thoughts and discussion back to the group.

• Identifying optimal tumor targets by evaluating density, internalization, and off-target risk
• Exploring current targets under development and their potential clinical impact
• Applying lessons from antibody-drug conjugates and other targeted therapies to guide RLT target selection

• Comparing antibodies, antibody fragments, peptides, and small molecules for different RLT applications
• Evaluating how moiety choice influences tumor uptake, internalization, and off-target exposure
• Applying practical lessons to match targeting format with clinical objectives and therapeutic strategy