Michael Groaning
Chief Scientific Officer Soricimed Biopharma Inc.
Seminars
Tuesday 21st July 2026
Workshop E
1:00 pm
Accurate dosimetry translation from animal models to humans is crucial for the safe and effective clinical application of targeted radiopharmaceuticals. This workshop delves into the methodologies, challenges, and best practices in extrapolating dosimetric data, ensuring that preclinical findings reliably inform human therapeutic strategies.
- Investigating a novel treatment approach in early phase clinical studies with the true theranostic pairs 61/67Cu-NU101 and 61/67Cu-NU201
- Comparing various extrapolation techniques and assessing their accuracy and applicability
- Review real-world examples where dosimetric translation informed clinical dosing, highlighting both successes and areas for improvement
- Leveraging in vivo (PET) and ex vivo biodistribution
- Dosimetry and scaling to human doses
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Outcome – Review the RWE for dosimetry informed clinical dosing – what went wrong, what could be improved and design an ideal phase zero trial.
Tuesday 21st July 2026
Selecting the Right Radioisotope: Maximizing Therapeutic Effect While Minimizing Risk
9:30 am
- Evaluating isotope properties including half-life and emission type
- Assessing radiochemical behavior for stability and efficacy
- Comparing isotopes for therapeutic versus diagnostic applications
Thursday 23rd July 2026
Lead Optimization: TRPV6-Targeted Radioligand Therapy & SAR Analysis for Optimal Ligand Decision Making
11:00 am
- Characterization of a novel target that expressed in several solid tumors
- Structure Activity Relationship (SAR) analysis in choosing best ligand to take into a Phase 0 clinical trial
