S. Sakura Minami
Vice President, Translational Medicine & Nonclinical Development Iron Fist Therapeutics
Seminars
Thursday 23rd July 2026
Panel Discussion: Shaping the Future of Combination Radioligand Therapy: Preclinical Perspectives
2:30 pm
- Balancing toxicity and efficacy: minimizing radiopharmaceutical dose while enhancing tumor kill
- Timing combination therapies: strategies for preclinical-to-clinical translation
- Selecting patients using biomarkers to match optimal RLT combinations with tumor and TME characteristics
Wednesday 22nd July 2026
Modulating Tumor Microenvironment– Mediated Resistance Mechanisms to Enhance Radiotherapy Response in Preclinical Models
2:00 pm
- Characterizing TME-driven resistance phenotypes, including autophagy, senescence, oxidative stress, angiogenesis, and immune modulation
- Mapping key signaling pathways linking TME dynamics to radioresistant cellular states
- Targeting the TME with preclinical interventions
